Computers and distributed software applications are becoming nowadays ubiquitous, and therefore their safety and reliability have increasingly important societal impact. In this context, formal methods equipped with powerful and versatile analysis tools are more important than ever in the design process. Despite the relevant scientific results and well-established tools obtained in recent years, there is a constant need of enhancing the analysis capabilities in order to handle increasingly complex systems. We briefly discuss some recent advances in the field, introducing five papers selected from the 22th International Conference on Tools and Algorithms for the Construction and Analysis of Systems (TACAS 2016).