Numerical investigation of particle aggregate steering with magnetic resonance navigation for targeted embolization - Inria - Institut national de recherche en sciences et technologies du numérique Accéder directement au contenu
Poster Année : 2022

Numerical investigation of particle aggregate steering with magnetic resonance navigation for targeted embolization

Résumé

Magnetic resonance navigation (MRN) has become a significant method to steer magnetized particles in medical applications by using MRI scanners. Dedicated MRN sequences have been successfully developed to track and steer such particle aggregates for selective chemoembolization of liver tumors. Particle aggregation is however a complex process and a comprehensive study of its shape and motion is needed to avoid damaging healthy tissues. Previous computational studies have considered non-aggregating particles or aggregates in 2D simplified settings. In this study, we investigate the forces acting on such micro-particle aggregation including drag, gravity, pressure gradient, virtual mass, magnetic gradient, dipole and contact forces. The code is developed in the OpenFOAM framework. Primary results are compared with bifurcation in vitro experimental data. Different sizes of clusters, directions of the magnetic field and gradient can be investigated to optimize aggregation form. This research represents an initial step towards complex in-vitro phantoms and in-vivo models.
Fichier non déposé

Dates et versions

hal-03938250 , version 1 (13-01-2023)

Identifiants

  • HAL Id : hal-03938250 , version 1

Citer

Mahdi Rezaei Adariani, Jiří Pešek, Ning Li, Charlotte Debbaut, Gilles Soulez, et al.. Numerical investigation of particle aggregate steering with magnetic resonance navigation for targeted embolization. 75th Annual Meeting of the Division of Fluid Dynamics, Nov 2022, Indianapolis, United States. ⟨hal-03938250⟩
56 Consultations
0 Téléchargements

Partager

Gmail Facebook X LinkedIn More