The growing importance of leveraging disruptive technologies is gaining prominence, while digitalizing smart cities. This paper is grounded in theory of disruptive technologies and seeks to develop and empirically test a comprehensive framework to leverage key disruptive technologies namely Internet of Things (IoT), Autonomous Vehicles (AV), Artificial General Intelligence (AGI) and 5G Networks (5G) for smart cities. Further, it not only identifies key disruptive technologies and the challenges while implementing them but also the benefits that the smart cities could attain by leveraging these disruptive technologies. With systematic literature review of 700 articles and using Structural Equation modelling (SEM) technique, to analyse the data collected from a sample of 575 industry practitioners and scholars, the results provide an appropriate model to leverage identified the disruptive technologies for smart cities. This article further provides implications for researchers, theories that govern smart cities and industry practitioners, while leveraging disruptive technologies of smart cities.