Cardiovascular (CV) diseases are leading cause of mortality and arterial stiffness is a very important risk marker. It can be obtained by non-invasive measurements of carotid-femoral pulse wave velocity (cfPWV), recommended as a gold-standard marker of CV risk by European Society of Cardiology (ESC). Previous works proved that arterial stiffness’s increase with ageing, sedentary lifestyle, smoking habits, etc. Central aortic pressure (CAP) is an important marker to evaluate blood pressure, in order to prevent cerebral vessels diseases, the most frequent causes of stroke and dementia. The present work reports a CAP and cfPWV data in order to characterize profile on different cohorts of Portuguese population: young adults with no associated diagnosis (NAD), adults with diagnosed axSpA and elderly with Sarcopenia. All measurements were performed using a novel, portable and low-cost device and developed protocol.