Improved 18-FDG PET/CT diagnosis of multiple myeloma diffuse disease by radiomics analysis
Abstract
In Multiple Myeloma (MM) patients, diffuse infiltration of bone marrow can be diagnosed on MRI and is associated with poorer prognosis. On 18-FDG PET/CT, the other important imaging modality in MM, the diagnosis of diffuse disease by visual analysis can be challenging. Radiomics allows the extraction of large amount of data from images to individualize disease specific diagnostic or prognostic patterns. We aimed todevelop a radiomics-based model derived from PET and CT images, that could improve the diagnosis of multiple myeloma diffuse disease on 18-FDG PET/CT.
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