Emergent vehicles will support a variety of connected applications, where a vehicle communicates with other vehicles or with the infrastructure to make a variety of decisions. Cooperative connected applications provide a critical foundational pillar for autonomous driving, and hold the promise of improving road safety, efficiency and environmental sustainability. However, they also induce a large and easily exploitable attack surface: an adversary can manipulate vehicular communications to subvert functionality of participating individual vehicles, cause catastrophic accidents, or bring down the transportation infrastructure. In this paper we outline a potential direction to address this critical problem through a resiliency framework, REDEM, based on machine learning. REDEM has several interesting features, including (1) smooth integration with the architecture of the underlying application, (2) ability to handle diverse communication attacks within the same underlying foundation, and (3) real-time detection and mitigation capability. We present the vision of REDEM, identify some key challenges to be addressed in its realization, and discuss the kind of evaluation/analysis necessary for its viability. We also present initial results from one instantiation of REDEM introducing resiliency in Cooperative Adaptive Cruise Control (CACC).