This paper presents the results from train-the-trainer workshop held for Tanzanian university faculty from four different universities. The aim of the workshop was to build entrepreneurial education capacity and competencies of local faculty. Findings from the workshop were planned to be integrated into the existing curricula of the universities together with activating and student-centred teaching methods. Main approaches were Problem based Learning and Design thinking.This was the first workshop in a multi-year project with main intention and focus set on innovative and entrepreneurial education from the perspective of knowledge, skills and mindset.The results show that participants of the workshop understood both at a general and at a context level how to add entrepreneurial practices and mindset to the natural sciences based curriculum. This was also the main aim of the workshop. Concerning educational content challenges there was more distribution among answers. Participants had different challenges concerning the topic. Process wise the practical and activating approach to the training was well understood and received. One of the main challenges was the question how to implement new approaches to the existing curricula.