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Communication Dans Un Congrès Année : 2019

Towards Validating Structural Connectivity in the Human Language System: An Intraoperative Cortico-Cortical Stimulation Experiment

Résumé

We aimed to validate structural connectivity measures based on diffusion MRI with Electrical Stimulation (ES) of the human brain cortex. For this, we combined white matter fiber tractography with propagation of Cortico-Cortical Evoked Potentials (CCEPs) induced by in-trasurgical ES in the language system of brain tumor patients. Our results showed high correlation (Pearson's coefficient 0.5-0.9) between delays of CCEPs and pathways connecting stimulation sites with recording electrodes. Our approach outperformed earlier study based on Diffusion Tensor Imaging. This potentially indicates that probabilistic tractogra-phy is an effective tool to quantify cortico-cortical communication non-invasively.
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Dates et versions

hal-02476639 , version 1 (13-02-2020)
hal-02476639 , version 2 (16-11-2020)

Identifiants

  • HAL Id : hal-02476639 , version 2

Citer

Patryk Filipiak, Fabien Almairac, Théodore Papadopoulo, Denys Fontaine, Lydiane Mondot, et al.. Towards Validating Structural Connectivity in the Human Language System: An Intraoperative Cortico-Cortical Stimulation Experiment. 27th Annual ISMRM 2019 - Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, May 2019, Montreal, Canada. ⟨hal-02476639v2⟩
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