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Article Dans Une Revue Physics in Medicine and Biology Année : 2018

3D-printed adaptive acoustic lens as a disruptive technology for transcranial ultrasound therapy using single-element transducers

Résumé

The development of multi-element arrays for better control of the shape of ultrasonic beams has opened the way for focusing through highly aberrating media, such as the human skull. As a result, the use of brain therapy with transcranial-focused ultrasound has rapidly grown. Although effective, such technology is expensive. We propose a disruptive, low-cost approach that consists of focusing a 1-MHz ultrasound beam through a human skull with a single-element transducer coupled with a tailored silicone acoustic lens cast in a 3D-printed mold and designed using computed tomography-based numerical acoustic simulation. We demonstrate on N=3 human skulls that adding lens-based aberration correction to a single-element transducer increases the deposited energy on the target 10 fold.
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Dates et versions

hal-02411212 , version 1 (14-12-2019)

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Guillaume Maimbourg, Alexandre Houdouin, Thomas Deffieux, Mickaël Tanter, Jean-François Aubry. 3D-printed adaptive acoustic lens as a disruptive technology for transcranial ultrasound therapy using single-element transducers. Physics in Medicine and Biology, 2018, 63 (2), pp.025026. ⟨10.1088/1361-6560/aaa037⟩. ⟨hal-02411212⟩
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