In accordance with data published from several related varieties of Mixtecan, and numerous other languages, Mixtepec-Mixtec body-part terms feature expansive networks of extended senses as the head component of a compound, in multi-word expressions and polysemous forms. Parts of the body which have given rise to other meanings in Mixtepec-Mixtec and/or in other forms of Mixtec are: ‘head,’ ‘face’, ‘back’ ’foot’, ‘leg’, ‘back’, ’hand/arm’, ‘belly/stomach’, ‘mouth’. Of these, as is the case in related Mixtecan varieties, ‘face’ and ‘foot’ are the most productive, as we will see, have undergone multiple stages of extensions.