Separation of existing audio into remixable elements is very useful to repurpose music audio. Applications include upmixing video soundtracks to surround sound (e.g. home theater 5.1 systems), facilitating music transcriptions, allowing better mashups and remixes for disk jockeys, and rebalancing sound levels on multiple instruments or voices recorded simultaneously to a single track. In this chapter, we provide an overview of the algorithms and approaches designed to address the challenges and opportunities in music. Where applicable, we also introduce commonalities and links to source separation for video soundtracks, since many musical scenarios involve video soundtracks (e.g. YouTube recordings of live concerts, movie sound tracks). While space prohibits describing every method in detail, we include detail on representative music‐specific algorithms and approaches not covered in other chapters. The intent is to give the reader a high‐level understanding of the workings of key exemplars of the source separation approaches applied in this domain.