fMRI Deconvolution via Temporal Regularization using a LASSO model and the LARS algorithm
Abstract
In the context of functional MRI (fMRI), methods based on the deconvolution of the blood oxygenated level dependent (BOLD) signal have been developed to investigate the brain activity, without a need of a priori knowledge about activations occurrence [2]. In this work, we propose a novel temporal regularized deconvolution of the BOLD signal using the Least Absolute Shrinkage and Selection Operator (LASSO) model, solved by means of the Least-Angle Regression (LARS) algorithm. In this way, we were able to recover the underlying neurons activations and their dynamics.
Domains
Signal and Image Processing| Origin | Files produced by the author(s) |
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