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Journal Articles IEEE Transactions on Medical Imaging Year : 2014

Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies

Ninon Burgos
M. J. Cardoso
  • Function : Author
K. Thielemans
  • Function : Author
M. Modat
  • Function : Author
S. Pedemonte
  • Function : Author
J. Dickson
  • Function : Author
A. Barnes
  • Function : Author
R. Ahmed
  • Function : Author
C. J. Mahoney
  • Function : Author
J. M. Schott
  • Function : Author
S. R. Arridge
  • Function : Author
B. F. Hutton
  • Function : Author

Abstract

Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.

Dates and versions

hal-01827217 , version 1 (01-07-2018)

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Cite

Ninon Burgos, M. J. Cardoso, K. Thielemans, M. Modat, S. Pedemonte, et al.. Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies. IEEE Transactions on Medical Imaging, 2014, 33 (12), pp.2332--2341. ⟨10.1109/TMI.2014.2340135⟩. ⟨hal-01827217⟩
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