A digital management system of cow diseases is presented in this paper, which based on standardization disease management framework. It can manage dairy cow disease from each stage including cow file creation, routine monitoring, disease prevention and control. Integrate electronic medical records was set up, which based on medical records include cow basic information and routine monitoring results and disease prevention information and can implement statistical analytic function of disease rate and guide cow immunization. The Unique numbers and integrated medical records information of every cow will lay the foundation for food of animal origin traceability. This system includes four subsystems, cow basic information management subsystem, cow individual health monitoring and evaluation subsystem, cow electronic medical records subsystem and cow disease prevention and control subsystem. With the help of system analysis and software design techniques, it is can manage cow disease on dairy farm effectually.