Nowadays, interoperability is essential to ensure the Product Lifecycle Management (PLM). However there are still some barriers to interoperability both technical and scientific which inhibit exchanges between the different information systems. This exchange can occur at different levels. In this paper the first one deals with exchanging and sharing information during the industrialization stage on the chain CAD-CAM-CNC. The second level developed concerns the chain of information systems materialized by the link between PDM-MPM-ERP. This paper identifies first the locks to interoperability and then explores the work done on those links with an interoperability point of view in order to remove the barriers identified.