In the software engineering community, research on domain-specific languages (DSLs) is focused on providing technologies for designing languages and tools that enable domain experts to develop system solutions eciently. Unfortunately, the current lack of support to explicitly relate concepts expressed in di↵erent DSLs makes it dicult for software and system engineers to reason about information distributed across models or programs describing di↵erent system aspects, at di↵er-ent levels of abstraction. Supporting the coordinated use of DSLs is what we call the globalization of DSLs. In this chapter, we introduce a grand challenge of the globalization of DSLs, and we present a few motivating scenarios for such a grand chalenge.