The field of Serious Games focus on the design, development, application and use of games for other purposes beyond entertainment. Education and training are the main application areas, but Serious Games have been successfully used in health, research, planning, emergency, and military advertising. Despite the evidence of efficacy, displayed also in this special edition, there is still limited use of Serious Games. This has mainly to do with social issues and stereotypes about the relationship of games and serious purposes. Initiatives like the SEGAN network that address the need to systematize the European approaches to Serious Games assume therefore great relevance. SEGAN is a Community of Practice to exchange ideas and experiences related to Serious Games. For instance, SEGAN can be the right place to extend the discussion on the high-quality articles that we present in this special edition about innovative approaches to Serious Games.