Postoperative recovery of hippocampal contralateral diffusivity in medial temporal lobe epilepsy correlates with memory functions. - Inria - Institut national de recherche en sciences et technologies du numérique Access content directly
Journal Articles Journal of Neurology, Neurosurgery and Psychiatry Year : 2011

Postoperative recovery of hippocampal contralateral diffusivity in medial temporal lobe epilepsy correlates with memory functions.

Abstract

This study aimed at determining if the recovery of mean diffusivity (MD) in the contralateral non sclerotic hippocampus is correlated with a change in memory outcome after surgery in patients with medial temporal lobe epilepsy (MTLE). Verbal and non-verbal memory scores and MD were assessed in 23 patients with MTLE before and after surgical treatment of epilepsy. The recovery of MD in the left hippocampus was correlated with the performance on verbal memory tests, and the recovery of MD in all patients was correlated with the performance on non-verbal memory tests. This finding strengthens the hypothesis that reversible diffusion abnormalities in the contralateral hippocampus in MTLE are linked to the active epileptic process that seems to interfere with memory abilities.

Domains

Medical Imaging

Dates and versions

hal-00795753 , version 1 (28-02-2013)

Identifiers

Cite

Micha Pfeuty, Lionel Thivard, Sophie Dupont, Claude Adam, Michel Baulac, et al.. Postoperative recovery of hippocampal contralateral diffusivity in medial temporal lobe epilepsy correlates with memory functions.. Journal of Neurology, Neurosurgery and Psychiatry, 2011, 82 (3), pp.340-3. ⟨10.1136/jnnp.2008.158428⟩. ⟨hal-00795753⟩
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