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Journal Articles ESAIM: Proceedings Year : 2010

OPTIMAL PLACEMENT OF ELECTRODES IN AN ELECTROPORATION PROCESS

Abstract

Electroporation consists in increasing the permeability of a tissue by applying high voltage pulses. In this paper we discuss the question of optimal placement and optimal loading of electrodes such that electroporation holds only in a given open set of the domain. The electroporated set of the domain is where the norm of the electric field is above a given threshold value. We use a standard gradient algorithm to optimize the loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order to move the electrodes. We also discuss the choice of objective functions to be chosen in the gradient algorithm.

Dates and versions

inria-00544874 , version 1 (09-12-2010)

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Cite

Nicolae Cindea, Benoît Fabrèges, Frédéric de Gournay, Clair Poignard. OPTIMAL PLACEMENT OF ELECTRODES IN AN ELECTROPORATION PROCESS. ESAIM: Proceedings, 2010, 30, pp.34-43. ⟨10.1051/proc/2010004⟩. ⟨inria-00544874⟩
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