Acute Changes in P-Wave Morphology by Pulmonary Vein Isolation in Atrial Fibrillation Patients - Inria - Institut national de recherche en sciences et technologies du numérique Access content directly
Conference Papers Year : 2018

Acute Changes in P-Wave Morphology by Pulmonary Vein Isolation in Atrial Fibrillation Patients

Abstract

Pulmonary vein (PV) plays an important role in atrial fibrillation (AF) initiation, progression, and stability. Successful PV isolation (PVI), either by radiofrequency catheter or Cryoballoon ablation, may terminate AF and prevent its recurrence. Whereas, incomplete PV isolation or reconnection of isolated PVs underlies mechanisms of AF recurrence. Hence, defining parameters able to predict a successful PVI and detect reconnections can assist clinicians in treatment of AF patients. Here, we developed a highly detailed human atrial model to simulate PVI and its acute effect on the P-wave morphology. Afterwards, the simulation results were compared and validated by recorded ECGs from patients before and after PVI procedure. In both simulation data and clinical recordings, we observed morphological changes in P-wave after PVI. More importantly our simulation helped us to find electrode positions in which the differences in P-wave morphology before and after PVI were more pronounced.
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Dates and versions

hal-01910663 , version 1 (01-11-2018)

Identifiers

  • HAL Id : hal-01910663 , version 1

Cite

Ali Gharaviri, Matthias Zink, Mark Potse, Simone Pezzuto, Stef Zeemering, et al.. Acute Changes in P-Wave Morphology by Pulmonary Vein Isolation in Atrial Fibrillation Patients. Computing in Cardiology, Sep 2018, Maastricht, Netherlands. ⟨hal-01910663⟩
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