CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine - Inria - Institut national de recherche en sciences et technologies du numérique Access content directly
Journal Articles Blood Advances Year : 2018

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine

Abstract

Key Points Ara-C is the mainstay of treatment for patients with AML, and life-threatening toxicities are common. We demonstrated that cytidine deaminase downregulation predicts severe/lethal toxicities with cytarabine.

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Cancer
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Dates and versions

hal-01770057 , version 1 (18-04-2018)

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Raphaelle Fanciullino, Laure Farnault, Mélanie Donnette, Diane-Charlotte Imbs, Catherine Roche, et al.. CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine. Blood Advances, 2018, 2 (5), pp.462 - 469. ⟨10.1182/bloodadvances.2017014126⟩. ⟨hal-01770057⟩
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