Current advancements in the business arena necessitate more than ever before the alignment of The Business and IT in organizations, which has been acknowledged as a complex issue to address. Our research is aimed at systematically addressing the linkage between business strategy and information systems (IS). We propose a model-driven approach for alignment, by leveraging the influence of established business strategy formulations from Strategic Management, and model-driven principles used within IS. The objective of this paper is to present the results of an empirical investigation carried out in Sweden on the linkage seeking to obtain insights from practitioners about the relevance of the problem, as well as of our model-driven proposal to address it.