The 2014 SIAM Workshop on Combinatorial Scientific Computing, held at the École Normale Supérieure in Lyon, France, July 21–23, was the sixth in a series that began ten years ago in San Francisco. True to CSC tradition, the 2014 workshop program comprised a wide range of combinatorial topics arising from many corners of scientific computing. Presenting recent results were a diverse set of speakers––PhD students, postdocs, early-career researchers, and well-established researchers, from academia, national laboratories, and industry; speakers from industry accounted for more than 10% of the talks. We give a summary of the meeting.