Modelling adipocytes size distribution - Inria - Institut national de recherche en sciences et technologies du numérique
Article Dans Une Revue Journal of Theoretical Biology Année : 2013

Modelling adipocytes size distribution

Résumé

Adipocytes are cells whose task is to store excess energy as lipid droplets in their cytoplasm. Adipocytes can adapt their size according to the lipid amount to be stored. Adipocyte size variation can reach one order of magnitude inside the same organism which is unique among cells. A striking feature in adipocytes size distribution is the lack of characteristic size since typical size distributions are bimodal. Since energy can be stored and retrieved and adipocytes are responsible for these lipid fluxes, we propose a simple model of size-dependent lipid fluxes that is able to predict typical adipocytes size distribution.

Dates et versions

hal-00850474 , version 1 (06-08-2013)

Identifiants

Citer

H. A. Soula, H. Julienne, Christophe Soulage, Alain Geloen. Modelling adipocytes size distribution. Journal of Theoretical Biology, 2013, 332, pp.89-95. ⟨10.1016/j.jtbi.2013.04.025⟩. ⟨hal-00850474⟩
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