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Journal Articles Journal of Theoretical Biology Year : 2013

Modelling adipocytes size distribution

Abstract

Adipocytes are cells whose task is to store excess energy as lipid droplets in their cytoplasm. Adipocytes can adapt their size according to the lipid amount to be stored. Adipocyte size variation can reach one order of magnitude inside the same organism which is unique among cells. A striking feature in adipocytes size distribution is the lack of characteristic size since typical size distributions are bimodal. Since energy can be stored and retrieved and adipocytes are responsible for these lipid fluxes, we propose a simple model of size-dependent lipid fluxes that is able to predict typical adipocytes size distribution.

Dates and versions

hal-00850474 , version 1 (06-08-2013)

Identifiers

Cite

H. A. Soula, H. Julienne, Christophe Soulage, Alain Geloen. Modelling adipocytes size distribution. Journal of Theoretical Biology, 2013, 332, pp.89-95. ⟨10.1016/j.jtbi.2013.04.025⟩. ⟨hal-00850474⟩
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