In this work we present a general framework for process-oriented coordination and collaboration in humanitarian operations. Process management has been proven useful in many business domains, but humanitarian operations and disaster response management in general require different process management approaches. Related work has only recently introduced traditional process management approaches for emergency management. These traditional approaches have several limitations with respect to the domain of humanitarian operations and disaster management. Our approach points to design, run-time and monitoring of inter-organizational humanitarian logistics processes. It consists of two parts: A reference model for humanitarian logistics tasks and a system for ad-hoc process management of these tasks. We discuss how they can be integrated to provide additional benefits