We describe in this article a framework for disaster response process management. This framework can be used to develop information systems sup- porting those processes. It is grounded in several research approaches: literature research, case studies, end user interviews and workshops. We compare disaster response process management with business process management and argue why it is substantial different to it. Another main result of this comparison is that busi- ness process management technology, such as flexible workflow systems, are not suitable for disaster response processes. We propose an information system sup- porting disaster response processes based on our developed framework. Finally we present validation of the information system design and give outlook on our future research.