Mobile Ad Hoc Networks (MANET) are spontaneous wireless networks of mobile nodes without any fixed infrastructure. MANET are promised to a large spectrum of military or civilian utilizations. Routing is a key topic in such networks: overhead must be minimized, optimizing the delay and reducing the packet losses. Several routing protocols were proposed in the literature but, recently, new routing protocols based on a self-organization, like Virtual Structure Routing (VSR), were proposed. VSR is based on a self-organized structure with an important stability and persistence. In this paper, we aim to quantify the contribution of the self-organization on the routing behavior and performances. We oppose VSR as a self-organized protocol to the classical one: reactive (AODV), proactive (OLSR) and clustered (CBRP). The impact of the mobility and the density, the horizontal and the vertical scalabilities are studied.