Mapping applications onto heterogeneous platforms is a difficult challenge, even for simple application patterns such as pipeline graphs. The problem is even more complex when processors are subject to failure during the execution of the application. In this paper, we study the complexity of a bi-criteria mapping which aims at optimizing the latency (i.e., the response time) and the reliability (i.e., the probability that the computation will be successful) of the application. Latency is minimized by using faster processors, while reliability is increased by replicating computations on a set of processors. However, replication increases latency (additional communications, slower processors). The application fails to be executed only if all the processors fail during execution. While simple polynomial algorithms can be found for fully homogeneous platforms, the problem becomes NP-hard when tackling heterogeneous platforms. This is yet another illustration of the additional complexity added by heterogeneity.