This paper reflects on what differentiates AI ethics issues from more general concerns raised by all IS applications. Examination of the PAPA framework advanced in 1986 by Richard Mason suggests that the categories of problems remains much as they have over the decades, with the exception of a new set of societal issues. Within these categories, however, the increase in capabilities of computing generally and AI in particular, shift some affordances from only possible to realized and the ethical issues attached to these affordances come to the fore. AI, however, is a catalyst for deeper philosophical considerations about the nature of mind, thought, agency, and responsibility.