Simulation has a pivotal role in the Industry 4.0 revolution as a tool to support the decision-making process in the production system. In this paper the model developed for an assembly line of EDM machines is presented and its use to improve the production management approach is described. In particular, simulation has been used to identify a better approach for the dispatching of new job to the line, to optimize the scheduling plan and to develop a training plan for the operators. Obtained results are promising and a further development of the model is foreseen.