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Conference Papers Year : 2021

Optimal bacterial resource allocation

Abstract

The problem of synthesizing a metabolite of interest in continuous bioreac- tors through resource allocation control is addressed. The approach is based on a self-replicator dynamical model that accounts for microbial culture growth inside the bioreactor, and incorporates a synthetic growth switch that allows to externally modify the RNA polymerase concentration of the bacterial popula- tion. The optimal control problem exhibits two ubiquitous phenomena: Fuller and turnpike. Joint work with J.-L. Gouzé and A. Yabo (Sophia).
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Dates and versions

hal-03528000 , version 1 (17-01-2022)

Identifiers

  • HAL Id : hal-03528000 , version 1

Cite

Agustin Gabriel Yabo, Jean-Baptiste Caillau, Jean-Luc Gouzé. Optimal bacterial resource allocation. DCO 2021 - International Conference on Dynamic Control and Optimization, Feb 2021, Aveiro, Portugal. ⟨hal-03528000⟩
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