One of the challenges faced by designers when creating technology is to be aware of social responsibilities when proposing a new digital artefact. With the popularization of computational technology among children, the challenge gains new proportions. Varied digital solutions have been presented for children at hospitals to lessen anxiety, stress and loneliness caused by hospitalization. If designers do not consider the broader view of the context, the social consequences of the use of their solutions might worsen users’ initial situation. In order to better understand the context and obtain a more comprehensive view from the state of the art in this subject, we used a Semiotic Framework and the Principles for Affectibility to analyze artefact solutions proposed for hospitalized children. As a result, we identified gaps that represent new opportunities for research. The results are discussed towards more social awareness towards new, contemporary interfaces that defy traditional interaction forms.