The NV-tree is a scalable approximate high-dimensional indexing method specifically designed for large-scale visual instance search. In this paper, we report on three experiments designed to evaluate the performance of the NV-tree. Two of these experiments embed standard benchmarks within collections of up to 28.5 billion features, representing the largest single-server collection ever reported in the literature. The results show that indeed the NV-tree performs very well for visual instance search applications over large-scale collections.