This work presents a modelling and a simulation of a pH control for process management in a drinking water treatment plant. A range of historical data, or knowledge base, was used to define the behavior of each input and disturbances of the process, using the MATLAB/Simulink software. The present pH control modelling has been simulated and compared to some experimental tests, thus contributing to achieve and identify operational scenarios in a real water treatment plant. Therefore, the present results allows to predict not only the present scenarios but also new operational conditions, in order to estimate the better process parameters and reduce some costs related to raw materials, such as the lime consumption, in water treatment plants.