Based on the total production process of iron and steel plant, and with the general design requirements for the major operating units, the major operating sites’ overall layout relationship of the iron and steel plant is determined. Based on the production workshops, auxiliary plants, power plants, transportation facilities, the functions of departments, subsidiary production and living services departments’ within and outside association, the situation of materials’ into and out, systematic optimization layout planning is proposed. With the size and position relationship of the operating units, and other relative limiting condition and common practices, overall layout design of the factory is developed.