Adding cognitive capabilities to the wireless networks makes it possible to leverage the control and management information used in the network operation to infer information about the local state and exploit it to improve the overall performance. This paper deals with the combined use of centralized and distributed cognitive cycles integrated at different planes in 5G networks: an integrated data plane, a unified control plane and a cross-layer management plane. This context-aware cognitive schema acts on the decision making modules depending on the monitored environment to prevent failures, balance the virtualized execution and get a global enhancement in the provision of mobile services. The multi-level cognitive cycle supports the interaction between the edge and the cloud blurring the line that separates two paradigms: centralized radio operation and mobile edge services.