For 40 years, the academics and business executives who have attended the Human Choice and Computers international conference series have discussed human choices and social responsibility in relation to information and communication technology (ICT). At this 2012 conference, the focus is on ICT critical infrastructures, and the challenges they pose to governments, businesses and people. Several topics have emerged as relevant in this conference: ICT developments at international and national levels; sustainable and responsible innovation; dilemmas involving ICT, peace and war; and the implications of ICT and social media for citizens’ involvement and citizens’ rights. What should national computing associations be doing to explore these serious issues? How should the International Federation for Information Processing (IFIP) itself respond? Responses are needed that are flexible and durable enough to face the challenges of the coming four decades.