In the paper a genetic algorithm approach to form potential Collaborative Networked Organizations (CNOs) is presented. When analyzing a set of companies that are potential partners of a CNO, it is possible to collect specific data from each company through which evaluate, once aggregated, for which Strategic Objective (SO) the potential aggregation is most suited. At this purpose a metric, consisting in a set of performance parameters related to different SO types, has been created. Given a large number of companies, through a genetic algorithm approach is then possible to set a specific objective function related to a particular SO (eg. maximize potential creation of new Business Opportunities), and to find the cluster (or clusters) of companies that maximizes the objective function.