System and method for personalized computation of tissue ablation extent based on medical images - Inria - Institut national de recherche en sciences et technologies du numérique Access content directly
Patents Year : 2015

System and method for personalized computation of tissue ablation extent based on medical images

Abstract

A method and system for personalized computation of tissue ablation extent based on medical images of a patient is disclosed. A patient-specific anatomical model of the liver and liver vessels is estimated from medical image data of a patient. Blood flow in the liver and liver vessels is simulated. An ablation simulation is performed that uses a bio-heat model to simulate heat diffusion due to an ablation based on the simulated blood flow and a cellular necrosis model to simulate cellular necrosis in the liver based on the simulated heat diffusion. Personalized tissue parameters of the bio-heat model and the cellular necrosis model are estimated based on observed results of a preliminary ablation procedure. Planning of the ablation procedure is then performed using the personalized bio-heat equation and the cellular necrosis model. The model can be subsequently refined as more ablation observations are obtained.

Domains

Medical Imaging
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Dates and versions

hal-01253687 , version 1 (11-01-2016)

Identifiers

  • HAL Id : hal-01253687 , version 1

Cite

Chloé Audigier, Tommaso Mansi, Saikiran Rapaka, Ali Kamen, Viorel Mihalef, et al.. System and method for personalized computation of tissue ablation extent based on medical images. United States, Patent n° : US 2015/0242588 A1. 2015. ⟨hal-01253687⟩

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