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Structure: Internal structure identifier : 411232

Creation of Three-dimensional Liver Tissue Models from Experimental Images for Systems Medicine

Stefan Hoehme , Adrian Friebel , Seddik Hammad , Dirk Drasdo , Jan G. Hengstler et al.
Peggy Stock, Bruno Christ. Hepatocyte Transplantation, 1506, Springer, pp.319-362, 2017, Methods in Molecular Biology, 978-1-4939-6504-5 (Print) 978-1-4939-6506-9. ⟨10.1007/978-1-4939-6506-9_22⟩
Book sections hal-01426722v1
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Guided interactive image segmentation using machine learning and color-based image set clustering

Adrian Friebel , Tim Johann , Dirk Drasdo , Stefan Hoehme
Bioinformatics, 2022, 38 (19), pp.4622-4628. ⟨10.1093/bioinformatics/btac547⟩
Journal articles hal-03702928v1
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Examining the Effects of Height, Velocity and Emotional Representation of a Social Transport Robot and Human Factors in Human-Robot Collaboration

Jana Jost , Thomas Kirks , Stuart Chapman , Gerhard Rinkenauer
17th IFIP Conference on Human-Computer Interaction (INTERACT), Sep 2019, Paphos, Cyprus. pp.517-526, ⟨10.1007/978-3-030-29384-0_31⟩
Conference papers hal-02544598v1

The Promise of Stochastic Resonance in Falls Prevention

Olivier White , Jan Babič , Carlos Trenado , Leif Johannsen , Nandu Goswami et al.
Frontiers in Physiology, 2019, ⟨10.3389/fphys.2018.01865⟩
Journal articles hal-02141876v1

The virtual liver: state of the art and future perspectives

Dirk Drasdo , Johannes Bode , Uta Dahmen , Olaf Dirsch , Steven Dooley et al.
Archives of Toxicology, 2014, pp.2071-2075. ⟨10.1007/s00204-014-1384-6⟩
Journal articles hal-01110684v1
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A digital twin of liver predicts regeneration after drug-induced damage at the level of cell type orchestration

Jieling Zhao , Ahmed Ghallab , Reham Hassan , Steven Dooley , Jan G Hengstler et al.
Preprints, Working Papers, ... hal-03738207v1
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A predictive computational model shows that biomechanical cell cycle progression control can explain liver regeneration after partial hepatectomy

Stefan Hoehme , Jan Boettger , Seddik Hammad , Brigitte Begher-Tibbe , Petru Bucur et al.
Preprints, Working Papers, ... hal-03136097v1
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Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

Ahmed Ghallab , Geraldine Celliere , Sebastian Henkel , Dominik Driesch , Stefan Hoehme et al.
Journal of Hepatology, 2015, 64 (4), pp.860-871. ⟨10.1016/j.jhep.2015.11.018⟩
Journal articles hal-01257127v1
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In-vitro to in-vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmaco-dynamic models and a multiscale spatial-temporal liver twin

Jules Dichamp , Geraldine Cellière , Ahmed Ghallab , Reham Hassan , Noemie Boissier et al.
Frontiers in Bioengineering and Biotechnology, In press, 11, ⟨10.3389/fbioe.2023.1049564⟩
Journal articles hal-03941544v1

Méthodes in silico et modélisation des mécanismes de toxicité (AOP)

Enrico Mombelli , Irene Vignon-Clementel , Dirk Drasdo
Francelyne Marano; Philippe Hubert; Laure Geoffroy; Hervé Juin. Quelles alternatives en expérimentation animale ?, Éditions Quae, pp.186, 2020, Savoir Faire, 978-2-7592-3187-4
Book sections hal-03135317v1

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Ahmed Ghallab , Ute Hofmann , Selahaddin Sezgin , Nachiket Vartak , Reham Hassan et al.
Hepatology, 2019, 69 (2), pp.666-683. ⟨10.1002/hep.30213⟩
Journal articles hal-02425193v2
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Towards a systematic use of effect biomarkers in population and occupational biomonitoring

M. Zare Jeddi , N.B. Hopf , S. Viegas , A.B. Price , A. Paini et al.
Environment International, 2021, 146, pp.106257. ⟨10.1016/j.envint.2020.106257⟩
Journal articles hal-03102593v1
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Ep-CAM RNA expression predicts metastasis-free survival in three cohorts of untreated node-negative breast cancer

Marcus Schmidt , Ilka Brigitte Petry , Daniel Böhm , Antje Lebrecht , Christian Törne et al.
Breast Cancer Research and Treatment, 2010, 125 (3), pp.637-646. ⟨10.1007/s10549-010-0856-5⟩
Journal articles hal-00561313v1

Visuospatial Processing in Memory for Word Location in Writing

Nathalie Le Bigot , Jean-Michel Passerault , Thierry Olive
Experimental Psychology, 2012, 59 (3), pp.138-146. ⟨10.1027/1618-3169/a000136⟩
Journal articles hal-02396463v1

Human response to simulated airport noise scenarios in home-like environments

Jacques Lambert , Patricia Champelovier , Régis Blanchet , Catherine Lavandier , Jonathan Terroir et al.
Applied Acoustics, 2015, 90, pp. 116-125. ⟨10.1016/j.apacoust.2014.11.009⟩
Journal articles hal-01228093v1
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A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues

Paul Van Liedekerke , Johannes Neitsch , Tim Johann , Enrico Warmt , Ismael Gonzàlez-Valverde et al.
Biomechanics and Modeling in Mechanobiology, 2019, ⟨10.1007/s10237-019-01204-7⟩
Journal articles hal-01956023v2
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A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures

Irene Vignon-Clementel , Nick Jagiella , Jules Dichamp , Jérôme Kowalski , Wiltrud Lederle et al.
Frontiers in Bioinformatics, 2023, 3, ⟨10.3389/fbinf.2023.977228⟩
Journal articles hal-04068296v1

Mental representations of magnitude and order: A dissociation by sensorimotor learning

Arnaud Badets , Arnaud Boutin , Herbert Heuer
Acta Psychologica, 2015, 157, pp.164-175. ⟨10.1016/j.actpsy.2015.03.004⟩
Journal articles hal-02091069v1
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Design of Game-Based Virtual Forests for Psychological Stress Therapy

Nur Ain Mohamad Yahaya , Dayang Rohaya Awang Rambli , Suziah Sulaiman , Frédéric Merienne , Emad Alyan et al.
Forests, 2023, 14 (2), pp.288. ⟨10.3390/f14020288⟩
Journal articles hal-04002448v1

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Patricio Godoy , Nicola J Hewitt , Ute Albrecht , Melvin E Andersen , Nariman Ansari et al.
Archives of Toxicology, 2013, 87 (8), pp.1315-530. ⟨10.1007/s00204-013-1078-5⟩
Journal articles hal-00939009v1

TiQuant: software for tissue analysis, quantification and surface reconstruction

Adrian Friebel , Johannes Neitsch , Tim Johann , Seddik Hammad , Dirk Drasdo et al.
Bioinformatics, 2015, 31 (19), pp.3234-3236. ⟨10.1093/bioinformatics/btv346⟩
Journal articles hal-01257137v1

Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling

Kai Markus Schneider , Lena Susanna Candels , Johannes Hov , Maiju Myllys , Reham Hassan et al.
Nature Metabolism, 2021, 3 (9), pp.1228-1241. ⟨10.1038/s42255-021-00452-1⟩
Journal articles hal-03505821v1
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Influence of cell mechanics in embryonic bile duct lumen formation: insight from quantitative modeling

Paul van Liedekerke , Lila Gannoun , Axelle Loriot , Frédéric P Lemaigre , Dirk Drasdo et al.
Preprints, Working Papers, ... hal-03135722v1
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Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

Estefanie Dufey , José Manuel Bravo-San Pedro , Cristian Eggers , Matías González-Quiroz , Hery Urra et al.
Nature Communications, 2020, 11 (1), pp.2401. ⟨10.1038/s41467-020-15694-y⟩
Journal articles hal-02862260v1
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Model prediction and validation of an order mechanism controlling the spatio-temporal phenotype of early hepatocellular carcinoma

François Bertaux , Stefan Hoehme , William Weens , Bettina Grasl-Kraupp , Jan G. Hengstler et al.
Preprints, Working Papers, ... hal-01426629v1

Model Prediction and Validation of an Order Mechanism Controlling the Spatiotemporal Phenotype of Early Hepatocellular Carcinoma

Stefan Hoehme , François Bertaux , William Weens , Bettina Grasl-Kraupp , Jan Hengstler et al.
Bulletin of Mathematical Biology, 2018, 80 (5), pp.1134-1171
Journal articles hal-01968844v1

Effects of Handedness on Visual Sensitivity in Perihand Space

Nathalie Le Bigot , Marc Grosjean
PLoS ONE, 2012, 7 (8), pp.e43150. ⟨10.1371/journal.pone.0043150⟩
Journal articles hal-03484223v1

Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis.

Seddik Hammad , Stefan Hoehme , Adrian Friebel , Iris von Recklinghausen , Amnah Othman et al.
Archives of Toxicology, 2014, 88 (5), pp.1161-1183. ⟨10.1007/s00204-014-1243-5⟩
Journal articles hal-01110657v1
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Modulating Portal Hemodynamics With Vascular Ring Allows Efficient Regeneration After Partial Hepatectomy in a Porcine Model.

Petru O. Bucur , Mohamed Bekheit , Chloe Audebert , Amnah Othman , Seddik Hammad et al.
Annals of Surgery, 2017, ⟨10.1097/SLA.0000000000002146⟩
Journal articles hal-01494844v1

How predictive quantitative modeling of tissue organization can inform liver disease pathogenesis.

Dirk Drasdo , Stefan Hoehme , Jan G. Hengstler
Journal of Hepatology, 2014, 61 (4), pp.951-956. ⟨10.1016/j.jhep.2014.06.013⟩
Journal articles hal-01110644v1