Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method. - Inria - Institut national de recherche en sciences et technologies du numérique Access content directly
Journal Articles BMC Genomics Year : 2010

Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.

Abstract

Our multiple CART strategy proved to be an effective tool to identify new Wnt/beta-catenin pathway targets based on the study of their regulatory regions in the human genome. In particular, several of these genes represent a new group of transcriptional dependent targets of the canonical Wnt pathway. The functions of these genes indicate that they are involved in pathophysiology related to Alzheimer's disease or other brain disorders.

Dates and versions

inria-00547316 , version 1 (16-12-2010)

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Christian Hödar, Rodrigo Assar, Marcela Colombres, Andrés Aravena, Leonardo Pavez, et al.. Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.. BMC Genomics, 2010, 11, pp.348. ⟨10.1186/1471-2164-11-348⟩. ⟨inria-00547316⟩
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