The Silene latifolia genome and its giant Y chromosome - Inria - Institut national de recherche en sciences et technologies du numérique
Preprints, Working Papers, ... (Preprint) Year : 2023

The Silene latifolia genome and its giant Y chromosome

1 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558
2 ICIn - UOH - Instituto de Ciencias de la Ingenieria
3 iBio - Instituto Milenio de Biología Integrativa = Millennium Institute for Integrative Biology
4 CIBIO - Centro de Investigação em Biodiversidade e Recursos Genéticos [Vairao]
5 FCUP - Faculdade de Ciências da Universidade do Porto
6 BIOPOLIS - Program in Genomics, Biodiversity and Land Planning
7 ESE - Ecologie Systématique et Evolution
8 VUB - Vrije Universiteit Brussel [Bruxelles]
9 IBP / CAS - Institute of Biophysics of the Czech Academy of Sciences
10 CEFE - Centre d’Ecologie Fonctionnelle et Evolutive
11 IPS2 (UMR_9213 / UMR_1403) - Institut des Sciences des Plantes de Paris-Saclay
12 UCPH - University of Copenhagen = Københavns Universitet
13 IRISA - Institut de Recherche en Informatique et Systèmes Aléatoires
14 CSU - Colorado State University [Fort Collins]
15 GENOSCOPE - Genoscope - Centre national de séquençage [Evry]
16 DTAMB - Développement de Techniques et Analyse Moléculaire de la Biodiversité [Lyon]
17 UMR AGAP - Amélioration génétique et adaptation des plantes méditerranéennes et tropicales
18 EBC - Department of Ecology and Genetics [Uppsala]
19 EFOR Group
20 EGCE - Evolution, génomes, comportement et écologie
21 Columbia University [New York]
22 SVQV - Santé de la vigne et qualité du vin
23 University of Louisville School of Medicine [Louisville]
24 IEB / CAS - Institute of Experimental Botany of the Czech Academy of Sciences
25 University of Virginia
26 TTU - Texas Tech University [Lubbock]
27 Indiana University [Bloomington]
28 JACOB - Institut de Biologie François JACOB
29 Institute of Evolutionary Biology, Ashworth Laboratories
Quentin Rougemont
Paris Veltsos
Amine Chebbi
  • Function : Author
Djivan Prentout
Amandine Velt
Matthew S. Olson
Deborah Charlesworth
Tatiana Giraud

Abstract

Abstract: In some species, the Y is a tiny chromosome but the dioecious plant Silene latifolia has a giant ∼550 Mb Y chromosome, which has remained unsequenced so far. Here we used a hybrid approach to obtain a high-quality male S. latifolia genome. Using mutants for sexual phenotype, we identified candidate sex-determining genes on the Y. Comparative analysis of the sex chromosomes with outgroups showed the Y is surprisingly rearranged and degenerated for a ∼11 MY-old system. Recombination suppression between X and Y extended in a stepwise process, and triggered a massive accumulation of repeats on the Y, as well as in the non-recombining pericentromeric region of the X, leading to giant sex chromosomes. One-Sentence Summary: This work uncovers the structure, function, and evolution of one of the largest giant Y chromosomes, that of the model plant Silene latifolia , which is almost 10 times larger than the human Y, despite similar genome sizes.

Dates and versions

hal-04293712 , version 1 (19-11-2023)

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Carol Moraga, Catarina Branco, Quentin Rougemont, Paris Veltsos, Pavel Jedlička, et al.. The Silene latifolia genome and its giant Y chromosome. 2023. ⟨hal-04293712⟩
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