Probiotic properties of non-conventional lactic acid bacteria: Immunomodulation by Oenococcus oeni - Inria - Institut national de recherche en sciences et technologies du numérique Accéder directement au contenu
Article Dans Une Revue International Journal of Food Microbiology Année : 2010

Probiotic properties of non-conventional lactic acid bacteria: Immunomodulation by Oenococcus oeni

Résumé

The widely used probiotic bacteria belong to the genera Lactobacillus and Bifidobacterium and have in most cases been isolated from the human gastrointestinal tract. However, other “less conventional” bacteria, from allochthonous or extremophilic origin, sharing similar structural or functional features, may also confer specific health benefits to a host. Firstly, we explored the in vitro immuno-modulatory or immune-stimulatory activities of 25 wine lactic acid bacteria belonging to Oenococcus oeni and Pediococcus parvulus. While cytokines released by peripheral blood mononuclear cells (PBMCs) stimulated by P. parvulus strains, showed little variation, O. oeni strains induced strain-specific cytokine patterns. Some O. oeni strains were then further analyzed under various conditions for growth, dose and culture medium. In a second phase, we evaluated the oral tolerance and safety of two strains of O. oeni in mice fed a high dose of bacteria for a week. Finally, evidence was gathered on the in vivo anti-inflammatory potential of a selected O. oeni strain using an experimental 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model. Although results did not match the anti-inflammatory levels obtained with certain conventional probiotics, strain IOEB 9115 significantly lowered colonic injury and alleviated colitis symptoms. The ‘natural’ tolerance towards acid, ethanol, and phenolic compounds of O. oeni strains combined with a measureable immunomodulatory potential, suggest a possible use of selected strains isolated from wine as live probiotics.
Fichier non déposé

Dates et versions

hal-02668586 , version 1 (31-05-2020)

Identifiants

Citer

Benoit Foligne, Joelle Dewulf, Jérôme Breton, Olivier Claisse, Aline Lonvaud-Funel, et al.. Probiotic properties of non-conventional lactic acid bacteria: Immunomodulation by Oenococcus oeni. International Journal of Food Microbiology, 2010, 140 (2-3), pp.136-145. ⟨10.1016/j.ijfoodmicro.2010.04.007⟩. ⟨hal-02668586⟩
21 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More