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              <p>Dans le cas de la recherche contre le VIH, lorsque la sensibilité d’une technique de dosage utilisée pour quantifier la charge virale, est faible, certaines valeurs sont censurées à gauche. Il existe un seuil de quantification analytique, en dessous duquel la valeur exacte de la mesure n’est pas connue, les concentrations sont dites indétectables. Cependant, même incomplètes, ces données apportent de l’information et méritent d’être conservées dans l’analyse. Nous proposons une comparaison par simulation de différents algorithmes proposés dans la littérature qui prennent en compte la censure dans une étude de grande dimension et dont les implémentations sont disponibles. Les méthodes ont été adaptées à l’hypothèse de données censurées gaussiennes.</p>
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