Microstructure driven tractography in the human brain
Abstract
Introduction: Diffusion-weighted (DW) magnetic resonance imaging (MRI) tractography has become the tool of choice to probe the human brain's
white matter (WM) in vivo. However, the relationship between the resulting streamlines and underlying WM microstructure
characteristics, such as axon diameter, remains poorly understood. In this work, we reconstruct human brain fascicles using a new
approach to trace WM fascicles while simultaneously characterizing the apparent distribution of axon diameters within the fascicle. This
provides the mean to estimate the microstructure characteristics of fascicles while improving their reconstruction in complex tissue
configurations.
Domains
Imaging
Origin : Files produced by the author(s)
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