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Instrumentation et méthodologies pour les études cérébrales in vivo sur modèles animaux : mesure cinétiques de radiotraceurs et imageries optiques en champ large.

Frederic Pain
Optique / photonique. Université Paris Sud, 2012
Habilitation à diriger des recherches tel-01316112v1
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Optical and thermal simulations for the design of optodes for minimally invasive optogenetics stimulation or photomodulation of deep and large cortical areas in non-human primate brain

Albertine Dubois , Chih-Chieh Chiang , F. Smekens , S. Jan , V Cuplov et al.
Journal of Neural Engineering, 2018, 15 (6), pp.065004. ⟨10.1088/1741-2552/aadf97⟩
Journal articles hal-01929085v1
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Visualizing odor representation in the brain: a review of imaging techniques for the mapping of sensory activity in the olfactory glomeruli

Frederic Pain , B. L’heureux , H. Gurden
Cellular and Molecular Life Sciences, 2011, 68 (16), pp.2689 - 2709. ⟨10.1007/s00018-011-0708-4⟩
Journal articles hal-01694184v1
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Correlative nonlinear optical microscopy and infrared nanoscopy reveals collagen degradation in altered parchments

Gaël Latour , Laurianne Robinet , Alexandre Dazzi , François Portier , Ariane Deniset-Besseau et al.
Scientific Reports, 2016, 6, pp.26344 ⟨10.1038/srep26344⟩
Journal articles hal-01321012v1
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Experimental assessment of the safety and potential efficacy of high irradiance photostimulation of brain tissues

Suhan Senova , Ilona Sisniak , Chih-Chieh Chiang , Isabelle Doignon , Stéphane Palfi et al.
Scientific Reports, 2017, 7, pp.43997. ⟨10.1038/srep43997⟩
Journal articles hal-01624076v1
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Simulation of nanoparticle-mediated near-infrared thermal therapy using GATE

Vesna Cuplov , Frederic Pain , Sébastien Jan
Biomedical optics express, 2017, 8 (3), pp.1665-1681. ⟨10.1364/BOE.8.001665⟩
Journal articles hal-01624184v1

Simultaneous microstructural and mechanical characterization of human corneas at increasing pressure

Aurélie Benoit , Gaël Latour , Schanne-Klein Marie-Claire , Jean-Marc Allain
Journal of the mechanical behavior of biomedical materials, 2016, 60, pp.93-105. ⟨10.1016/j.jmbbm.2015.12.031⟩
Journal articles in2p3-02025078v1
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Predicting the Location of Glioma Recurrence After a Resection Surgery

Erin Stretton , Emmanuel Mandonnet , Ezequiel Geremia , Bjoern H. Menze , Hervé Delingette et al.
Proceedings of 2nd International MICCAI Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data (STIA'12), 2012, Nice, France. ⟨10.1007/978-3-642-33555-6_10⟩
Conference papers hal-00813870v1
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In vivo quantification of localized neuronal activation and inhibition in the rat brain using a dedicated high temporal-resolution β+-sensitive microprobe

Frederic Pain , Laurent Besret , Françoise Vaufrey , M.-C. Gregoire , Laurent Pinot et al.
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99 (16), pp.10807 - 10812. ⟨10.1073/pnas.162368899⟩
Journal articles hal-01624226v1
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Development and evaluation of an intraoperative beta imaging probe for radio-guided solid tumor surgery

Sara Spadola
Medical Physics []. Université Paris Saclay (COmUE), 2016. English. ⟨NNT : 2016SACLS257⟩
Theses tel-01500096v1

SiPM arrays and miniaturized readout electronics for compact gamma camera

N. Dinu , T. Imando , A. Nagai , L. Pinot , V. Puill et al.
7th International Conference on New Developments in Photodetection (NDIP 14), Jul 2014, Tours, France. pp.367-372, ⟨10.1016/j.nima.2015.01.083⟩
Conference papers in2p3-01018180v1

Miniaturized Multi-Channels SiPM Read-Out Electronics for the Development of Compact Gamma Cameras

V. Vandenbussche , T. Imando , N. Dinu , L. Pinot , S. Callier et al.
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, and Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors workshop,, Oct 2013, Seoul, South Korea
Conference poster in2p3-00875956v1
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Experimental and analytical comparative study of optical coefficient of fresh and frozen rat tissues

Mohammed Mesradi , Aurelie Genoux , Vesna Cuplov , Darine Abi Haidar , Sebastien Jan et al.
Journal of Biomedical Optics, 2013, ⟨10.1117/1.JBO.18.11.117010⟩
Journal articles hal-01316109v1

An Intraoperative Positron Imaging Probe Based on Silicon Photomultipliers Dedicated to the Control of Tumor Margins During Radioguided Cancer Surgery

S. Spadola , N. Hudin , L. Pinot , B. Janvier , C. Esnault et al.
2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (2014 NSS/MIC), and 21st Symposium on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Nov 2014, Seattle, United States
Conference poster in2p3-01082121v1

New concept of a submillimetric pixellated Silicon detector for intracerebral application

M. Benoit , J. Märk , P. Weiss , D. Benoit , J.C. Clemens et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2011, 659, pp.499-503. ⟨10.1016/j.nima.2011.08.027⟩
Journal articles istex in2p3-00618519v1
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Multispectral reflectance imaging of brain activation in rodents: methodological study of the differential path length estimations and first in vivo recordings in the rat olfactory bulb

Rémi Renaud , Claire Martin , Hirac Gurden , Frederic Pain
Journal of Biomedical Optics, 2012, 17 (1), ⟨10.1117/1.JBO.17.1.016012⟩
Journal articles hal-01316107v1

Imagerie Compton en protonthérapie : de la simulation GATE à la reconstruction d'images

E. Hilaire , Cédric Robert Robert , X. Lojacono , C. Lartizien , I. Buvat et al.
XXIVème Colloque GRETSI - Traitement du Signal et des Images (GRETSI'13), Sep 2013, Brest, France
Conference papers hal-00850529v1

Potential High Resolution Dosimeters For MRT

E. Bräuer-Krisch , A. Rosenfeld , M. Lerch , M. Petasecca , M. Akselrod et al.
6th International Conference on Medical Applications of Synchrotron Radiation - AIP Conference, 2010, Melbourne, Australia
Conference papers hal-01940094v1
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Extension of the GATE Monte-Carlo simulation package to model bioluminescence and fluorescence imaging

Vesna Cuplov , Iréne Buvat , Frederic Pain , Sébastien Jan
Journal of Biomedical Optics, 2014, ⟨10.1117/1.JBO.19.2.026004⟩
Journal articles hal-01316110v1
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Tissue database of autofluorescence response to improve intra-operative diagnosis of primitive brain tumors

Fanny Poulon
Optics / Photonic. Université Paris Saclay (COmUE), 2018. English. ⟨NNT : 2018SACLS236⟩
Theses tel-02343182v1

Compton imaging in proton therapy: reconstructed image of the simulated prompt-γ distribution

E. Hilaire , Cédric Robert Robert , X. Lojacono , D. Sarrut , I. Buvat et al.
ICTR-PHE 2014, Feb 2014, Genève, Switzerland. pp.S43
Conference papers hal-01052717v1

Development and Performance Characterization of Intraoperative Positron Probes for Tumor Surgery

N. Hudin , L. Pinot , B. Janvier , Y. Charon , M.-A. Duval et al.
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, and Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors workshop, Oct 2013, Seoul, South Korea
Conference papers in2p3-00876539v1

Functional ultrasound imaging reveals different odor-evoked patterns of vascular activity in the main olfactory bulb and the anterior piriform cortex

Frederic Pain , F. Osmanski , C. Martin , G. Montaldo , P. Laniece et al.
NeuroImage, 2014, 95, pp.176 - 184. ⟨10.1016/j.neuroimage.2014.03.054⟩
Journal articles hal-01624079v1
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Comparison of different segmentation approaches without using gold standard. Application to the estimation of the left ventricle ejection fraction from cardiac cine MRI sequences.

Jessica Lebenberg , Irène Buvat , Mireille Garreau , Christopher Casta , Constantin Constantinidès et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society., Aug 2011, Boston, United States. pp.2663-6, ⟨10.1109/IEMBS.2011.6090732⟩
Conference papers inserm-00773261v1
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Electrophysiological brain mapping: Basics of recording evoked potentials induced by electrical stimulation and its physiological spreading in the human brain

Marion Vincent , David Guiraud , Hugues Duffau , Emmanuel Mandonnet , François Bonnetblanc et al.
Clinical Neurophysiology, 2017, 128 (10), pp.1886-1890. ⟨10.1016/j.clinph.2017.07.402⟩
Journal articles hal-01613032v2
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A method based on Monte Carlo simulations and voxelized anatomical atlases to evaluate and correct uncertainties on radiotracer accumulation quantitation in beta microprobe studies in the rat brain

Frederic Pain , Marc Dhenain , Hirac Gurden , Anne-Lise Routier , Françoise Lefebvre et al.
Physics in Medicine and Biology, 2008, 53 (19), pp.5385 - 5404. ⟨10.1088/0031-9155/53/19/008⟩
Journal articles hal-01694187v1